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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its efficacy or increasing the risk of side effects.

  1. : Though not a direct interaction, combining Cialis with other medications like other nitrates (e.g., nitroglycerin) with concomitant use of Tadalafil and nitrates can worsen side effects like dizziness or fainting could include additional alpha-blockers or beta-blockers that can increase the risk of hypotension.
  2. Rifampicin: Though not a direct interaction, combining Cialis with other medications like other nitrates (e.g., nitroglycerin) with concomitant use of tadalafil and nitrates can worsening side effects like increased heart rate or sudden dizziness in sensitive individuals.

Cialis has been shown to cause some mild side effects. Talk to your health care provider if these do not go away within a few days. If you begin to experience more serious reactions, seek medical attention immediately.

Common side effects reported from Cialis use include:

  • Headache
  • Indigestion
  • Heartburn
  • Upset stomach
  • Gas
  • Nausea
  • Flushing

More severe side effects include:

  • Painful erections or erections that last longer than 4 hours
  • Sudden loss of vision
  • Sudden loss of hearing
  • Ringing in the ears
  • Chest pain
  • Shortness of breath
  • Painful urination
  • Increased urination frequency
  • Fainting
  • Dizziness
  • Skin rash
  • Hives
  • Facial swelling

If you experience any of these side effects, seek medical attention immediately. These are symptoms of a severe adverse reaction to this medication that require immediate treatment.

As with all prescription medications, inform your doctor of any medical conditions you currently manage. Tell them about any and all medications, prescription drugs, and supplements you are taking before starting treatment with Cialis. Cialis can interact with bodily substances, causing potentially serious adverse reactions.

Specifically, you should inform your health care provider of any alpha-blocker, antifungal, HIV protease inhibitor, or high blood pressure medication you are taking. Remember to mention any herbal products you use, especially St. John’s wort.

In addition, let your doctor know if you have recently had heart surgery or experience chest pain during sex. If you experience any changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

Read More About Cialis..Play Video where it says. Share ThisVideo:

As with most medications, Cialis can cause a mild rash, flushing, and parasites. These symptoms are typically mild and go away when your sexual health care provider is away from roombound.

PlayVideo How to Take Cialis..
  • Tangentially, Cialis can cause a sudden loss of vision in one or both eyes during normal vision vision co-ordination. Both eyes can now have a black, tint to their vision.
  • Angling of the eyelids
  • Thriving
  • Bleeding
  • Pain in the upper lid of the eye
  • Pain during sexual intercourse
  • In addition to the mentioned side effects, there is a possibility of more serious reactions when taking Cialis include:

    • An erection that lasts more than 4 hours
    • Sudden loss of hearing in some individuals
    • Sudden dizziness
    • Stomach pain
    • Sudden back pain

    If you experience any serious health concerns, it is important to contact your doctor before you take Cialis. A healthcare professional may need to adjust the dosage or recommend alternative treatment options.

    If you experience changes in your heartbeat or chest pain during sex, contact your health care provider immediately.

  • Both eyes can now have a black, tint to their eye.
  • Erectile Dysfunction

    Erection problems (impotence) are very common, particularly in men over 40.

    Most men occasionally fail to get or keep an erection. This is usually due to stress, tiredness, anxiety or drinking too much alcohol, and it’s nothing to worry about.

    If it happens more often, it may be caused by physical or emotional problems.

    Physical causes Possible cause Treatment Narrowing of penis blood vessels, high blood pressure, high cholesterol medicine to lower blood pressure, statins to lower cholesterol Hormone problems hormone replacement – for example, testosterone Side effects of prescribed medication change to medicine following discussion with GP You may also be asked to make lifestyle changes.

    Do lose weight if you’re overweight stop smoking eat a healthy diet exercise daily try to reduce stress and anxiety

    Don’t cycle for a while (if you cycle more than 3 hours a week) drink more than 14 units of alcohol a week

  • Side Effects

    Possible side effects

    Like all medicines, this medicine can cause side effects, although not everybody gets them. These effects are normally mild to moderate in nature.

    If you experience any of the following side effects stop using the medicine and seek medical help immediately:

    allergic reactions including rashes (frequency uncommon). chest pain – do not use nitrates but seek immediate medical assistance (frequency uncommon). priapism, a prolonged and possibly painful erection after taking CIALIS (frequency rare). If you have such an erection, which lasts continuously for more than 4 hours you should contact a doctor immediately. sudden loss of vision (frequency rare). Other side effects have been reported:

    Common (seen in 1 to 10 in every 100 patients)

    headache, back pain, muscle aches, pain in arms and legs, facial flushing, nasal congestion, and indigestion. Uncommon (seen in 1 to 10 in every 1,000 patients)

    dizziness, stomach ache, feeling sick, being sick (vomiting), reflux, blurred vision, eye pain, difficulty in breathing, presence of blood in urine, prolonged erection, pounding heartbeat sensation, a fast heart rate, high blood pressure, low blood pressure, nose bleeds, ringing in the ears, swelling of the hands, feet or ankles and feeling tired. Rare (seen in 1 to 10 in every 10,000 patients)

    fainting, seizures and passing memory loss, swelling of the eyelids, red eyes, sudden decrease or loss of hearing, hives (itchy red welts on the surface of the skin), penile bleeding, presence of blood in semen and increased sweating. Heart attack and stroke have also been reported rarely in men taking CIALIS. Most of these men had known heart problems before taking this medicine.

    Partial, temporary, or permanent decrease or loss of vision in one or both eyes has been rarely reported.

  • Authiliation Name - Cialis® Medication Type of Medication

    CIALIS is a medication that works by increasing blood flow to the penis. It is taken by mouth.

    CIALIS is usually prescribed in the dose and duration as follows:

    - Dose 1 – 10mg taken orally, once a day. - Dose 10 – 20mg taken orally once a day, every day. - Dose 30 – 40mg taken orally once a day, every day for 7 days.

    - Dose 1.25 – 2.5mg/kg body weight taken orally, once a day. - Dose 15 – 30mg/kg body weight taken orally, every day for 7 days.

    - Dose 15 – 45mg/kg body weight taken orally, every day for 7 days.

    - Dose 30 – 45mg/kg body weight taken orally, every day for 7 days.

    - Dose 45 – 60mg/kg body weight taken orally, every day for 7 days.

    - Dose 60 – 90mg/kg body weight taken orally, every day for 7 days.

    - A 2.5mg/kg daily strength of CIALIS taken at the same time of day can be used to achieve the same effect as the 5mg dose.

  • Like all medicines, CIALIS can cause side effects, although not everybody gets them.

  • What is Cialis?

    Cialis, or the generic name of the drug, is one of the most popular erectile dysfunction (ED) medicines available. With its active ingredient Tadalafil, it is a medication that is taken to treat erectile dysfunction. It has been approved by the FDA for the treatment of ED and has been shown to help men achieve and maintain a firm erection during sexual activity.

    What is the use of Cialis?

    It is a generic version of Cialis, which means that it is approved by the FDA to treat ED. The active ingredient of Cialis, Tadalafil, is a phosphodiesterase inhibitor that is part of the PDE-5 enzyme, which is the blood flow to the penis, helping to achieve and maintain an erection. In addition, men who have high blood pressure or heart failure may be able to achieve and maintain a firm erection for up to 36 hours after taking Cialis.

    How does Cialis work?

    Cialis is an erectile dysfunction drug that works by increasing blood flow to the penis. This helps men achieve and maintain an erection during sexual stimulation. Tadalafil, on the other hand, is a more potent PDE-5 inhibitor that works by relaxing the blood vessels and enhancing blood flow to the penis.

    Tadalafil is also used to treat pulmonary arterial hypertension (high blood pressure in the lungs) in patients who suffer from angina pectoris (chest pain).

    How long does it take for Cialis to work?

    Cialis is typically taken once a day, about 36 hours after taking the medication. It is important to note that Cialis may only work for up to 36 hours, meaning that the medication may not be fully effective at this time.

    What is the dosage of Cialis?

    The typical dosage of Cialis is one tablet of 20 mg taken once a day for up to 36 hours, or one tablet of 30 mg taken once a day for up to 36 hours. The doctor may adjust the dosage based on individual needs and response to the medication.

    What should I do if I miss a dose?

    If you miss a dose of Cialis, take it as soon as you remember. However, if it’s almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take a double dose to make up for the missed one.

    Can I take Cialis if I take any nitrate medications?

    Nitrate medications are not recommended for taking Cialis, as they can cause side effects like chest pain or flushing, which are not suitable for everyone. If you are using nitrates, talk to your doctor before taking Cialis if you have a history of heart disease or stroke. You can also take Cialis if you have a history of high or low blood pressure.

    What are the possible side effects of Cialis?

    The most common side effects of Cialis are headache, flushing, nasal congestion, and visual changes. However, these side effects are usually mild and temporary, and they can resolve on their own or be temporary. If you experience any severe side effects, like an erection lasting more than four hours or difficulty achieving orgasm, stop taking Cialis and contact your doctor immediately.

    Can I take Cialis with other medications?

    Some medications can interact with Cialis, including nitrates and alpha-blockers, which can increase the risk of side effects. If you have any questions about using Cialis, please speak with your doctor.

    However, if it's almost time for your next dose, skip the missed dose and go back to your regular dosing schedule.

    Does Cialis affect blood pressure?

    Cialis can cause low blood pressure that may be unsafe for some men. It may also cause side effects such as dizziness, headache, and nausea. If you experience any of these symptoms, stop taking Cialis and contact your doctor immediately.